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Building Polymorphisms
Genetic Polymorphisms of Monodelphis domestica: Several kinds of genetic polymorphisms have been described for the opossum model. Polymorphisms are listed below by category and links are provided to tables and corresponding publications and websites where information about these polymorphisms can be obtained.
Coding-gene polymorphisms
Protein polymorphisms: Information and references for coding-gene polymorphisms detected by protein electrophoresis techniques.
Download Polymorphisms PROTEIN.xls
DNA polymorphisms: Information and references for coding gene polymorphisms detected by PCR-based analyses.
Download Polymorphisms DNA.xls.
Anonymous polymorphisms
Short-tandem repeat (STR) polymorphisms: Information and references for short-tandem repeat (microsatellite) polymorphisms.
Download Polymorphisms MICROSATS.xls
Non-repeat DNA polymorphisms: Information and references for unique sequence anonymous DNA polymorphisms.
Download Polymorphisms NON_REPEAT.xls
Single nucleotide polymorphisms: A catalog of ~1.28 million potential single-nucleotide polymorphism (SNP) sites discovered in connection with the opossum genome project may be found at http://www.broad.mit.edu/mammals/opossum/snps.html. These putative SNPs were discovered by comparing reads from animals derived from different geographic origins with the sequence of the animal used to produce the genome assembly (MonDom5). The comparisons suggest an average SNP density in the range of one every 237 bp (1/237 bp) throughout the M. domestica genome, ranging from a low of 1/358 bp to a high of 1/140 bp depending on the animal compared. As expected, the frequency of SNPs correlates well with the geographic distance between the ancestral origins of test animals relative to that of the MonDom5 assembly animal.